| HMDBP01566 | Cytochrome P450 2A7 | P20853 | CYP2A7 | 19q13.2 | Unknown | Not Available |
| HMDBP01567 | Cytochrome P450 2A6 | P11509 | CYP2A6 | 19q13.2 | Unknown | Not Available |
| HMDBP01623 | Sex hormone-binding globulin | P04278 | SHBG | 17p13-p12 | Enzyme | Not Available |
| HMDBP01624 | Androgen receptor | P10275 | AR | | Enzyme | - Maudsley S, Davidson L, Pawson AJ, Freestone SH, Lopez de Maturana R, Thomson AA, Millar RP: Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5. Neuroendocrinology. 2006;84(5):285-300. Epub 2007 Jan 4. [PubMed:17202804 ]
- Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Small EJ, Ryan CJ: The case for secondary hormonal therapies in the chemotherapy age. J Urol. 2006 Dec;176(6 Pt 2):S66-71. [PubMed:17084172 ]
- Omwancha J, Brown TR: Selective androgen receptor modulators: in pursuit of tissue-selective androgens. Curr Opin Investig Drugs. 2006 Oct;7(10):873-81. [PubMed:17086931 ]
- Petraki CD, Sfikas CP: Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma. Histol Histopathol. 2007 Jan;22(1):107-18. doi: 10.14670/HH-22.107. [PubMed:17128417 ]
- Lapauw B, Goemaere S, Crabbe P, Kaufman JM, Ruige JB: Is the effect of testosterone on body composition modulated by the androgen receptor gene CAG repeat polymorphism in elderly men? Eur J Endocrinol. 2007 Mar;156(3):395-401. [PubMed:17322500 ]
|
| HMDBP02075 | Serum albumin | P02768 | ALB | 4q13.3 | Unknown | Not Available |
| HMDBP02101 | Multidrug resistance protein 1 | P08183 | ABCB1 | 7q21.12 | Transporter | - Polli JW, Wring SA, Humphreys JE, Huang L, Morgan JB, Webster LO, Serabjit-Singh CS: Rational use of in vitro P-glycoprotein assays in drug discovery. J Pharmacol Exp Ther. 2001 Nov;299(2):620-8. [PubMed:11602674 ]
- Katoh M, Nakajima M, Yamazaki H, Yokoi T: Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport. Eur J Pharm Sci. 2001 Feb;12(4):505-13. [PubMed:11231118 ]
|
| HMDBP02137 | Natriuretic peptides B | P16860 | NPPB | | Enzyme | Not Available |
| HMDBP02257 | ATP-binding cassette sub-family G member 2 | Q9UNQ0 | ABCG2 | 4q22 | Transporter | - Janvilisri T, Venter H, Shahi S, Reuter G, Balakrishnan L, van Veen HW: Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. J Biol Chem. 2003 Jun 6;278(23):20645-51. Epub 2003 Mar 28. [PubMed:12668685 ]
|
| HMDBP02439 | Solute carrier family 22 member 4 | Q9H015 | SLC22A4 | 5q31.1 | Transporter | - Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, Sabolic I, Koepsell H, Brockmoller J: The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin. Clin Pharmacol Ther. 2009 Sep;86(3):299-306. doi: 10.1038/clpt.2009.92. Epub 2009 Jun 17. [PubMed:19536068 ]
|
| HMDBP02550 | Sodium/bile acid cotransporter | Q14973 | SLC10A1 | 14q24.1 | Transporter | - Schroeder A, Eckhardt U, Stieger B, Tynes R, Schteingart CD, Hofmann AF, Meier PJ, Hagenbuch B: Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells. Am J Physiol. 1998 Feb;274(2 Pt 1):G370-5. [PubMed:9486191 ]
|
| HMDBP02574 | Solute carrier family 22 member 1 | O15245 | SLC22A1 | 6q26 | Transporter | - Wu X, Kekuda R, Huang W, Fei YJ, Leibach FH, Chen J, Conway SJ, Ganapathy V: Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain. J Biol Chem. 1998 Dec 4;273(49):32776-86. [PubMed:9830022 ]
|
| HMDBP02683 | Solute carrier organic anion transporter family member 1A2 | P46721 | SLCO1A2 | 12p12 | Transporter | - Lu R, Kanai N, Bao Y, Wolkoff AW, Schuster VL: Regulation of renal oatp mRNA expression by testosterone. Am J Physiol. 1996 Feb;270(2 Pt 2):F332-7. [PubMed:8779895 ]
- Kanai N, Lu R, Bao Y, Wolkoff AW, Vore M, Schuster VL: Estradiol 17 beta-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am J Physiol. 1996 Feb;270(2 Pt 2):F326-31. [PubMed:8779894 ]
- Bossuyt X, Muller M, Hagenbuch B, Meier PJ: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther. 1996 Mar;276(3):891-6. [PubMed:8786566 ]
|
| HMDBP02862 | 17-beta-hydroxysteroid dehydrogenase type 6 | O14756 | HSD17B6 | 12q13 | Unknown | Not Available |
| HMDBP04309 | Solute carrier family 22 member 3 | O75751 | SLC22A3 | 6q25.3 | Transporter | - Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, Sabolic I, Koepsell H, Brockmoller J: The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin. Clin Pharmacol Ther. 2009 Sep;86(3):299-306. doi: 10.1038/clpt.2009.92. Epub 2009 Jun 17. [PubMed:19536068 ]
|
| HMDBP04403 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 | P14060 | HSD3B1 | 1p13.1 | Unknown | Not Available |
| HMDBP04404 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 | P26439 | HSD3B2 | 1p13.1 | Unknown | Not Available |
| HMDBP07348 | UDP-glucuronosyltransferase 2A3 | Q6UWM9 | UGT2A3 | 4q13.2 | Enzyme | Not Available |
| HMDBP07417 | Cytochrome P450, family 1, subfamily A, polypeptide 1 | A0N0X8 | CYP1A1 | 15q24.1 | Enzyme | Not Available |
| HMDBP09068 | Solute carrier family 22 member 7 | Q9Y694 | SLC22A7 | 6p21.1 | Transporter | - Kobayashi Y, Hirokawa N, Ohshiro N, Sekine T, Sasaki T, Tokuyama S, Endou H, Yamamoto T: Differential gene expression of organic anion transporters in male and female rats. Biochem Biophys Res Commun. 2002 Jan 11;290(1):482-7. [PubMed:11779196 ]
|
| HMDBP09188 | Polyprenol reductase | Q9H8P0 | SRD5A3 | 4q12 | Enzyme | Not Available |
| HMDBP09238 | HCG2039726, isoform CRA_f | Q5DT02 | UGT1A10 | 2q37 | Enzyme | Not Available |
| HMDBP09239 | HCG2039726, isoform CRA_e | Q5DSZ6 | UGT1A8 | 2q37 | Enzyme | Not Available |
| HMDBP09240 | UDP glycosyltransferase 1 family polypeptide A7 | Q5DSZ7 | UGT1A7 | 2q37 | Enzyme | Not Available |
| HMDBP09335 | Cytochrome P450 2D6 | Q6NWU0 | CYP2D6 | 22q13.1 | Enzyme | Not Available |
