Hmdb loader

HMDBP00035 (Fatty acid synthase) Metabolite Associations

Displaying metabolite protein links 26 - 36 of 36 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB00107303-Oxotetradecanoic acidThumbC14H26O3242.3544
242.188194698		Not Available
HMDB0010732trans-Tetra-dec-2-enoic acidThumbC14H26O2226.355
226.193280076		Not Available
HMDB0000910Tridecanoic acid638-53-9ThumbC13H26O2214.3443
214.193280076		Not Available
HMDB0010728(R)-3-Hydroxydodecanoic acidThumbC12H24O3216.3172
216.172544634		Not Available
HMDB00107273-Oxododecanoic acidThumbC12H22O3214.3013
214.15689457		Not Available
HMDB0010729trans-Dodec-2-enoic acidThumbC12H22O2198.3019
198.161979948		Not Available
HMDB0015168Cerulenin17397-89-6ThumbC12H17NO3223.2683
223.120843415
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Oskouian B, Saba JD: YAP1 confers resistance to the fatty acid synthase inhibitor cerulenin through the transporter Flr1p in Saccharomyces cerevisiae. Mol Gen Genet. 1999 Mar;261(2):346-53. [PubMed:10102370 ]
  3. Li JN, Gorospe M, Chrest FJ, Kumaravel TS, Evans MK, Han WF, Pizer ES: Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer Res. 2001 Feb 15;61(4):1493-9. [PubMed:11245456 ]
  4. Heiligtag SJ, Bredehorst R, David KA: Key role of mitochondria in cerulenin-mediated apoptosis. Cell Death Differ. 2002 Sep;9(9):1017-25. [PubMed:12181752 ]
  5. Flavin R, Peluso S, Nguyen PL, Loda M: Fatty acid synthase as a potential therapeutic target in cancer. Future Oncol. 2010 Apr;6(4):551-62. doi: 10.2217/fon.10.11. [PubMed:20373869 ]
  6. Lupu R, Menendez JA: Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents? Curr Pharm Biotechnol. 2006 Dec;7(6):483-93. [PubMed:17168665 ]
  7. Ronnett GV, Kim EK, Landree LE, Tu Y: Fatty acid metabolism as a target for obesity treatment. Physiol Behav. 2005 May 19;85(1):25-35. [PubMed:15878185 ]
HMDB0001416Pantetheine 4'-phosphate2226-71-3ThumbC11H23N2O7PS358.348
358.096358302		Not Available
HMDB0010725(R)-3-Hydroxydecanoic acidThumbC10H20O3188.264
188.141244506		Not Available
HMDB00107243-Oxodecanoic acidThumbC10H18O3186.2481
186.125594442		Not Available
HMDB0010726trans-Dec-2-enoic acidThumbC10H18O2170.2487
170.13067982		Not Available
Displaying metabolite protein links 26 - 36 of 36 in total