Hmdb loader

HMDBP00126 (Aldehyde oxidase) Metabolite Associations

Displaying metabolite protein links 1 - 25 of 36 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0002217(S)-Methylmalonic acid semialdehyde99043-16-0ThumbC4H6O3102.0886
102.031694058		Not Available
HMDB00006991-Methylnicotinamide3106-60-3ThumbC7H9N2O137.1592
137.07148792		Not Available
HMDB00011722-Methyl-3-oxopropanoic acid6236-08-4ThumbC4H6O3102.0886
102.031694058		Not Available
HMDB00000174-Pyridoxic acid82-82-6ThumbC8H9NO4183.1614
183.053157781
  1. Stanulovic M, Jeremic V, Leskovac V, Chaykin S: New pathway of conversion of pyridoxal to 4-pyridoxic acid. Enzyme. 1976;21(4):357-69. [PubMed:939227 ]
HMDB00040735-Hydroxyindoleacetaldehyde1892-21-3ThumbC10H9NO2175.184
175.063328537		Not Available
HMDB00007635-Hydroxyindoleacetic acid54-16-0ThumbC10H9NO3191.1834
191.058243159		Not Available
HMDB02470536-DeoxypenciclovirThumbC10H15N5O2237.263
237.122574743		Not Available
HMDB0014581Allopurinol315-30-0ThumbC5H4N4O136.1115
136.03851077
  1. Moriwaki Y, Yamamoto T, Nasako Y, Takahashi S, Suda M, Hiroishi K, Hada T, Higashino K: In vitro oxidation of pyrazinamide and allopurinol by rat liver aldehyde oxidase. Biochem Pharmacol. 1993 Sep 14;46(6):975-81. [PubMed:8216357 ]
HMDB0001263Allysine6665-12-9ThumbC6H11NO3145.1564
145.073893223		Not Available
HMDB0014627Brimonidine59803-98-4ThumbC11H10BrN5292.135
291.011957992
  1. Acheampong AA, Chien DS, Lam S, Vekich S, Breau A, Usansky J, Harcourt D, Munk SA, Nguyen H, Garst M, Tang-Liu D: Characterization of brimonidine metabolism with rat, rabbit, dog, monkey and human liver fractions and rabbit liver aldehyde oxidase. Xenobiotica. 1996 Oct;26(10):1035-55. [PubMed:8905918 ]
HMDB0060462Citalopram aldehydeThumbC18H14FNO2295.3077
295.100856902		Not Available
HMDB0060463Citalopram propionic acidThumbC18H14FNO3311.3071
311.095771524		Not Available
HMDB0030788Citrusal5980-07-4ThumbC15H16O4260.2851
260.104859		Not Available
HMDB0001046Cotinine486-56-6ThumbC10H12N2O176.2151
176.094963016		Not Available
HMDB0031219Ethyl carbamate51-79-6ThumbC3H7NO289.0932
89.047678473
  1. Sugihara K, Kitamura S, Tatsumi K: Involvement of liver aldehyde oxidase in conversion of N-hydroxyurethane to urethane. J Pharmacobiodyn. 1983 Sep;6(9):677-83. [PubMed:6689178 ]
HMDB0001248FAD146-14-5ThumbC27H33N9O15P2785.5497
785.157134455		Not Available
HMDB0014570Famciclovir104227-87-4ThumbC14H19N5O4321.3318
321.143704121
  1. Rashidi MR, Smith JA, Clarke SE, Beedham C: In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver. Drug Metab Dispos. 1997 Jul;25(7):805-13. [PubMed:9224775 ]
  2. Al-Salmy HS: Inter-strain variability in aldehyde oxidase activity in the mouse. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Jul;132(3):341-7. [PubMed:12161167 ]
HMDB0004062Gentisate aldehyde1194-98-5ThumbC7H6O3138.1207
138.031694058		Not Available
HMDB0000152Gentisic acid490-79-9ThumbC7H6O4154.121
154.026608673		Not Available
HMDB0003178Heme14875-96-8ThumbC34H32FeN4O4616.487
616.177297665		Not Available
HMDB0059597Hydrogen IonThumbH1.0079
1.007825032		Not Available
HMDB0003125Hydrogen peroxide7722-84-1ThumbH2O234.0147
34.005479308		Not Available
HMDB0001892Menadione58-27-5ThumbC11H8O2172.18
172.0524295
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
HMDB0014703Methotrexate59-05-2ThumbC20H22N8O5454.4393
454.171315854
  1. Zientek M, Jiang Y, Youdim K, Obach RS: In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase. Drug Metab Dispos. 2010 Aug;38(8):1322-7. doi: 10.1124/dmd.110.033555. Epub 2010 May 5. [PubMed:20444863 ]
  2. Baggott JE, Morgan SL: Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation. Arthritis Rheum. 2009 Aug;60(8):2257-61. doi: 10.1002/art.24685. [PubMed:19644884 ]
  3. Jordan CG, Rashidi MR, Laljee H, Clarke SE, Brown JE, Beedham C: Aldehyde oxidase-catalysed oxidation of methotrexate in the liver of guinea-pig, rabbit and man. J Pharm Pharmacol. 1999 Apr;51(4):411-8. [PubMed:10385213 ]
HMDB0000202Methylmalonic acid516-05-2ThumbC4H6O4118.088
118.02660868		Not Available
Displaying metabolite protein links 1 - 25 of 36 in total