Hmdb loader

HMDBP00480 (UDP-glucuronosyltransferase 2B7) Metabolite Associations

Displaying metabolite protein links 26 - 50 of 164 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0031884Sandosaponin A135272-91-2ThumbC48H76O19957.117
956.498080227		Not Available
HMDB0010340Retinyl beta-glucuronideThumbC26H38O7462.5757
462.26175357
  1. Genchi G, Wang W, Barua A, Bidlack WR, Olson JA: Formation of beta-glucuronides and of beta-galacturonides of various retinoids catalyzed by induced and noninduced microsomal UDP-glucuronosyltransferases of rat liver. Biochim Biophys Acta. 1996 Mar 15;1289(2):284-90. [PubMed:8600986 ]
HMDB0003141Retinoyl b-glucuronide401-10-5ThumbC26H36O8476.5592
476.241018128
  1. Gestl SA, Green MD, Shearer DA, Frauenhoffer E, Tephly TR, Weisz J: Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers. Am J Pathol. 2002 Apr;160(4):1467-79. [PubMed:11943730 ]
HMDB0029214Quercetin-4'-glucuronide201463-36-7ThumbC21H18O13478.3598
478.074740662		Not Available
HMDB0029212Quercetin 3-O-glucuronide22688-79-5ThumbC21H18O13478.3598
478.074740662		Not Available
HMDB0010318Pregnanediol 3-O-glucuronide1852-49-9ThumbC27H44O8496.6335
496.303618384		Not Available
HMDB0010323Phenethylamine glucuronideThumbC14H19NO6297.3038
297.121237345		Not Available
HMDB0003402Pectin9000-69-5ThumbC6H10O7194.1394
194.042652674		Not Available
HMDB0003363Pectic acid9046-40-6ThumbC6H10O7194.1394
194.042652674		Not Available
HMDB0010331Palmitoyl glucuronideThumbC22H42O7418.5647
418.293053698		Not Available
HMDB0011686p-Cresol glucuronideThumbC13H16O7284.2619
284.089602866		Not Available
HMDB0010347Octanoylglucuronide99910-55-1ThumbC14H24O8320.3356
320.147117744		Not Available
HMDB0013989O-DesmethylnaproxenThumbC13H12O3216.2326
216.07864425
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
HMDB0060498NNAL-N-glucuronideThumbC16H24N3O8386.3771
386.156339759		Not Available
HMDB0001272Nicotine glucuronide152306-59-7ThumbC16H22N2O6338.3557
338.147786446
  1. Kaivosaari S, Toivonen P, Hesse LM, Koskinen M, Court MH, Finel M: Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. Mol Pharmacol. 2007 Sep;72(3):761-8. Epub 2007 Jun 18. [PubMed:17576790 ]
HMDB0033106N6-Galacturonyl-L-lysine220718-57-0ThumbC12H22N2O8322.3117
322.13761569		Not Available
HMDB0033105N2-Galacturonyl-L-lysine220718-56-9ThumbC12H22N2O8322.3117
322.13761569		Not Available
HMDB0015159Mycophenolic acid24280-93-1ThumbC17H20O6320.3371
320.125988372
  1. Picard N, Ratanasavanh D, Premaud A, Le Meur Y, Marquet P: Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism. Drug Metab Dispos. 2005 Jan;33(1):139-46. Epub 2004 Oct 6. [PubMed:15470161 ]
  2. Dostalek M, Court MH, Hazarika S, Akhlaghi F: Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite. Drug Metab Dispos. 2011 Mar;39(3):448-55. doi: 10.1124/dmd.110.036608. Epub 2010 Dec 1. [PubMed:21123165 ]
HMDB0014826Mycophenolate mofetil128794-94-5ThumbC23H31NO7433.4947
433.210052351
  1. Picard N, Ratanasavanh D, Premaud A, Le Meur Y, Marquet P: Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism. Drug Metab Dispos. 2005 Jan;33(1):139-46. Epub 2004 Oct 6. [PubMed:15470161 ]
HMDB0041937Morphine-6-glucuronide20290-10-2ThumbC23H27NO9461.4618
461.168581467		Not Available
HMDB0041936Morphine-3-glucuronide20290-09-9ThumbC23H27NO9461.4618
461.168581467		Not Available
HMDB0014440Morphine57-27-2ThumbC17H19NO3285.3377
285.136493479
  1. Abildskov K, Weldy P, Garland M: Molecular cloning of the baboon UDP-glucuronosyltransferase 2B gene family and their activity in conjugating morphine. Drug Metab Dispos. 2010 Apr;38(4):545-53. doi: 10.1124/dmd.109.030635. Epub 2010 Jan 13. [PubMed:20071451 ]
  2. Coffman BL, Rios GR, King CD, Tephly TR: Human UGT2B7 catalyzes morphine glucuronidation. Drug Metab Dispos. 1997 Jan;25(1):1-4. [PubMed:9010622 ]
  3. Takeda S, Ishii Y, Iwanaga M, Mackenzie PI, Nagata K, Yamazoe Y, Oguri K, Yamada H: Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4. Mol Pharmacol. 2005 Mar;67(3):665-72. Epub 2004 Dec 20. [PubMed:15611481 ]
  4. Yamada H, Ishii K, Ishii Y, Ieiri I, Nishio S, Morioka T, Oguri K: Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain. J Toxicol Sci. 2003 Dec;28(5):395-401. [PubMed:14746343 ]
HMDB0015382Mitiglinide145375-43-5ThumbC19H25NO3315.4067
315.183443671
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
HMDB0031965Melilotussaponin O1ThumbC53H86O221075.2367
1074.561074436		Not Available
HMDB0013847Losartan N2-glucuronideThumbC28H31ClN6O7599.035
598.194275083		Not Available
Displaying metabolite protein links 26 - 50 of 164 in total