Hmdb loader

HMDBP00480 (UDP-glucuronosyltransferase 2B7) Metabolite Associations

Displaying metabolite protein links 101 - 125 of 164 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0002061Hyaluronic acid9004-61-9Thumb(C14H21NO11)nH2ONot Available
Not Available
HMDB0001390Hydroxycotinine34834-67-8ThumbC10H12N2O2192.2145
192.089877638
  1. Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T: Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes. Drug Metab Dispos. 2005 Jan;33(1):23-30. Epub 2004 Oct 6. [PubMed:15470160 ]
HMDB0010343Ibuprofen glucuronide98649-76-4ThumbC19H26O8382.409
382.162767797
  1. Kuehl GE, Lampe JW, Potter JD, Bigler J: Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug Metab Dispos. 2005 Jul;33(7):1027-35. Epub 2005 Apr 20. [PubMed:15843492 ]
HMDB0002704Iduronic acid3402-98-0ThumbC6H10O7194.1394
194.042652674		Not Available
HMDB0010319Indoxyl glucuronide35804-66-1ThumbC14H15NO7309.2714
309.084851839		Not Available
HMDB0002091Isovalerylglucuronide88070-93-3ThumbC11H18O8278.2558
278.100167552		Not Available
HMDB0031656Jaceidin 4'-glucuronideThumbC24H24O14536.439
536.116605476		Not Available
HMDB0029500Kaempferol 3-glucuronide22688-78-4ThumbC21H18O12462.3604
462.07982604		Not Available
HMDB0010334Ketoprofen glucuronide76690-94-3ThumbC22H22O9430.4047
430.126382302
  1. Kuehl GE, Lampe JW, Potter JD, Bigler J: Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes. Drug Metab Dispos. 2005 Jul;33(7):1027-35. Epub 2005 Apr 20. [PubMed:15843492 ]
HMDB0031353Kudzusaponin SA4179910-78-2ThumbC47H74O20959.0785
958.477344808		Not Available
HMDB0031959Lablaboside DThumbC60H94O281263.3716
1262.593162424		Not Available
HMDB0031960Lablaboside EThumbC66H106O321411.5286
1410.666721296		Not Available
HMDB0031961Lablaboside F208390-15-2ThumbC66H106O311395.5292
1394.671806674		Not Available
HMDB0002513Lithocholate 3-O-glucuronide75239-91-7ThumbC30H48O9552.6967
552.329833134		Not Available
HMDB0013847Losartan N2-glucuronideThumbC28H31ClN6O7599.035
598.194275083		Not Available
HMDB0031965Melilotussaponin O1ThumbC53H86O221075.2367
1074.561074436		Not Available
HMDB0015382Mitiglinide145375-43-5ThumbC19H25NO3315.4067
315.183443671
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
HMDB0014440Morphine57-27-2ThumbC17H19NO3285.3377
285.136493479
  1. Abildskov K, Weldy P, Garland M: Molecular cloning of the baboon UDP-glucuronosyltransferase 2B gene family and their activity in conjugating morphine. Drug Metab Dispos. 2010 Apr;38(4):545-53. doi: 10.1124/dmd.109.030635. Epub 2010 Jan 13. [PubMed:20071451 ]
  2. Coffman BL, Rios GR, King CD, Tephly TR: Human UGT2B7 catalyzes morphine glucuronidation. Drug Metab Dispos. 1997 Jan;25(1):1-4. [PubMed:9010622 ]
  3. Takeda S, Ishii Y, Iwanaga M, Mackenzie PI, Nagata K, Yamazoe Y, Oguri K, Yamada H: Modulation of UDP-glucuronosyltransferase function by cytochrome P450: evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4. Mol Pharmacol. 2005 Mar;67(3):665-72. Epub 2004 Dec 20. [PubMed:15611481 ]
  4. Yamada H, Ishii K, Ishii Y, Ieiri I, Nishio S, Morioka T, Oguri K: Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain. J Toxicol Sci. 2003 Dec;28(5):395-401. [PubMed:14746343 ]
HMDB0041936Morphine-3-glucuronide20290-09-9ThumbC23H27NO9461.4618
461.168581467		Not Available
HMDB0041937Morphine-6-glucuronide20290-10-2ThumbC23H27NO9461.4618
461.168581467		Not Available
HMDB0014826Mycophenolate mofetil128794-94-5ThumbC23H31NO7433.4947
433.210052351
  1. Picard N, Ratanasavanh D, Premaud A, Le Meur Y, Marquet P: Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism. Drug Metab Dispos. 2005 Jan;33(1):139-46. Epub 2004 Oct 6. [PubMed:15470161 ]
HMDB0015159Mycophenolic acid24280-93-1ThumbC17H20O6320.3371
320.125988372
  1. Picard N, Ratanasavanh D, Premaud A, Le Meur Y, Marquet P: Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism. Drug Metab Dispos. 2005 Jan;33(1):139-46. Epub 2004 Oct 6. [PubMed:15470161 ]
  2. Dostalek M, Court MH, Hazarika S, Akhlaghi F: Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite. Drug Metab Dispos. 2011 Mar;39(3):448-55. doi: 10.1124/dmd.110.036608. Epub 2010 Dec 1. [PubMed:21123165 ]
HMDB0033105N2-Galacturonyl-L-lysine220718-56-9ThumbC12H22N2O8322.3117
322.13761569		Not Available
HMDB0033106N6-Galacturonyl-L-lysine220718-57-0ThumbC12H22N2O8322.3117
322.13761569		Not Available
HMDB0001272Nicotine glucuronide152306-59-7ThumbC16H22N2O6338.3557
338.147786446
  1. Kaivosaari S, Toivonen P, Hesse LM, Koskinen M, Court MH, Finel M: Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. Mol Pharmacol. 2007 Sep;72(3):761-8. Epub 2007 Jun 18. [PubMed:17576790 ]
Displaying metabolite protein links 101 - 125 of 164 in total