Human Metabolome Database: Showing Protein Nucleoside diphosphate-linked moiety X motif 19, mitochondrial (HMDBP08780)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 metabolites

Identification

HMDB Protein ID

HMDBP08780

Secondary Accession Numbers

14503

Name

Nucleoside diphosphate-linked moiety X motif 19, mitochondrial

Synonyms

Nudix motif 19

Gene Name

NUDT19

Protein Type

Unknown

Biological Properties

General Function

Involved in hydrolase activity

Specific Function

Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched- chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates

Pathways

Not Available

Reactions

Not Available

GO Classification

Function
catalytic activity
hydrolase activity

Cellular Location

Mitochondrion
Peroxisome

Gene Properties

Chromosome Location

Chromosome:1

Locus

19q13.11

SNPs

NUDT19

Gene Sequence

>1128 bp
ATGAGCAGCTCCCTGCGGCCGGGCCCCAGCCGCTGGCGGCGGGCGGCCAGCATCGTCCTG
GCGGCTGGCTGGTCGCGCCCGGAGACCGCCACCCCGCCGTCGCGCCCGCCGCCGGCCGAG
GGCTTCCGGCTGCTGCTGCTGCAGCGCTCCCCGCACCAAGGCTTCATGCCGGGCGCGCAC
GTCTTCTCCGGCGGAGTGCTGGATGCGGCCGACCGCTCGGCGGACTGGCTGGGCCTCTTC
GCGCCGCACCACGGGCCGCCGCGCTTCGGCCTGGGCCCGGCGCCATTCAGCCGCACCGCT
TTCCCGTCGCTGCCCGACACCGATGACCACAAGACCGACAACACTGGGACGCTGCCTGAG
GACGTAGCCTTCCGCATCTGCGCCGTGCGGGAGGCCTTTGAGGAGGCGGGCGTGCTGCTG
CTGCGGCCCAGGACTTCCCCACCAGGCCCAGCACCCGGGCCTGGCCTCGCCCTGGAGCCA
CCGCCGGGCCTGGCCTCCTGGCGCGACCGCGTGCGCCAGGACCCGCGCCACTTCCTGCGG
CTGTGCGCCCACCTCGACTGCACACCCGACATCTGGGCGCTGCACAACTGGAGCGCCTGG
CTCACCCCTTTCTTGCGGGGCACCACTCGCCGCTTTGACACGGCCTTCTTCCTGTGCTGC
CTGCGCGAGCCGCCGCCCGTCTACCCCGACTTGGCGGAGGTGGTGGGCTACCAGTGGTCA
TCTCCATCAGAGGCAACTGAAAGTTTCTTATCAAAAGAAATTTGGTTGCCACCCCCACAG
TTCTACGAAGTGAGAAGACTTGCAAACTTTGCCTCTCTCTCTGACTTGCACAAATTTTGT
TTGGGTCGTGCATTAGAAGGACTGGAAAGGTGGCTGCCGATCATCTTGTTAACTGCTGAT
GGGATGGTCCATCTTTTACCAGGTGATGAGCTATATTTAGAAGATTCAGACTTTTTGGAA
AATCTTATGTCTACTGAAAAAAAGACTGAGGAAATCATGAAGGAAGGCAAGCAGTTTCAC
CGGATAGTGACATACCATCGCCACCTTTATGATATCCACGTGACTGTTCAGCCAAAGTAT
AAACACGTTTATCCTAAGAACTCTGTAGTAAGAAAAAGCCATTTGTAG

Protein Properties

Number of Residues

375

Molecular Weight

42232.8

Theoretical pI

7.7

Pfam Domain Function

NUDIX (PF00293 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Nucleoside diphosphate-linked moiety X motif 19, mitochondrial
MSSSLRPGPSRWRRAASIVLAAGWSRPETATPPSRPPPAEGFRLLLLQRSPHQGFMPGAH
VFSGGVLDAADRSADWLGLFAPHHGPPRFGLGPAPFSRTAFPSLPDTDDHKTDNTGTLPE
DVAFRICAVREAFEEAGVLLLRPRTSPPGPAPGPGLALEPPPGLASWRDRVRQDPRHFLR
LCAHLDCTPDIWALHNWSAWLTPFLRGTTRRFDTAFFLCCLREPPPVYPDLAEVVGYQWS
SPSEATESFLSKEIWLPPPQFYEVRRLANFASLSDLHKFCLGRALEGLERWLPIILLTAD
GMVHLLPGDELYLEDSDFLENLMSTEKKTEEIMKEGKQFHRIVTYHRHLYDIHVTVQPKY
KHVYPKNSVVRKSHL

External Links

GenBank ID Protein

157739940

UniProtKB/Swiss-Prot ID

A8MXV4

UniProtKB/Swiss-Prot Entry Name

NUD19_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM: The DNA sequence and biology of human chromosome 19. Nature. 2004 Apr 1;428(6982):529-35. [PubMed:15057824 ]