| Identification |
|---|
| HMDB Protein ID
| HMDBP10650 |
| Secondary Accession Numbers
| |
| Name
| Glycylpeptide N-tetradecanoyltransferase |
| Synonyms
|
Not Available
|
| Gene Name
| NMT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in glycylpeptide N-tetradecanoyltransferase activity |
| Specific Function
| Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring acyl groups |
| transferase activity, transferring acyl groups other than amino-acyl groups |
| acyltransferase activity |
| n-acyltransferase activity |
| glycylpeptide n-tetradecanoyltransferase activity |
| Process |
| metabolic process |
| macromolecule metabolic process |
| macromolecule modification |
| protein modification process |
| protein amino acid lipidation |
| n-terminal protein lipidation |
| n-terminal protein myristoylation |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10p13 |
| SNPs
| NMT2 |
| Gene Sequence
|
>1590 bp
ATGGCGGAGGACAGCGAGTCTGCGGCCAGCCAGCAGAGCCTGGAACTGGACGACCAGGAC
ACGTGCGGGATAGACGGGGACAATGAGGAGGAGACGGAGCACGCCAAAGGAAGTCCTGGA
GGGTATTTGGGAGCCAAAAAGAAAAAGAAGAAACAGAAGAGAAAAAAGGAGAAACCAAAT
TCCGGAGGCACCAAGTCAGACTCGGCATCTGATTCCCAGGAGATTAAAATTCAGCAGCCT
TCGAAACACAACACCATCTGGCAGCAGATTTCAGCGGGAGCAGCCATGGGTAGTGCTACT
ATGGAAGGTGAATGGACAGGCATGAGAAATGATCATAAGAATCCCAGTGTTCCAATGCAG
AAGTTGCAGGATATCCAGAGAGCAATGGAGCTGCTATCCGCATGCCAGGGCCCAGCCAGG
AACATTGATGAGGCTGCAAAGCACAGATACCAGTTTTGGGACACACAACCGGTACCAAAA
CTAGATGAAGTCATAACATCTCATGGTGCAATTGAACCAGATAAAGACAACGTACGCCAA
GAACCGTATTCTTTGCCACAGGGTTTTATGTGGGACACTTTAGACTTGAGTGATGCCGAA
GTGCTCAAGGAGTTATACACGTTGTTAAATGAGAATTACGTAGAAGATGATGACAATATG
TTCCGATTTGACTATTCACCCGAGTTCCTGTTGTGGGCTCTGCGTCCACCAGGCTGGCTC
CTGCAGTGGCACTGTGGGGTCAGAGTGTCTTCAAATAAAAAACTGGTCGGGTTCATAAGT
GCCATCCCAGCAAACATTCGGATTTATGACAGTGTGAAGAAGATGGTAGAAATCAACTTT
CTTTGTGTTCATAAGAAGTTGAGATCGAAACGGGTAGCCCCAGTGCTAATCCGAGAGATC
ACTAGAAGAGTGAACCTGGAAGGGATCTTCCAGGCTGTGTACACCGCGGGAGTGGTTCTT
CCTAAGCCCATAGCCACATGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTA
GAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATAC
AGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAA
TCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGAT
GAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTG
GAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTG
ATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACA
GAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTT
GATGTATTCAATGCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTT
GGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGAT
TCTGAAAAGGTTGGACTAGTACTACAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 529 |
| Molecular Weight
| 60378.5 |
| Theoretical pI
| 7.46 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glycylpeptide N-tetradecanoyltransferase
MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPN
SGGTKSDSASDSQEIKIQQPSKHNTIWQQISAGAAMGSATMEGEWTGMRNDHKNPSVPMQ
KLQDIQRAMELLSACQGPARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQ
EPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWL
LQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREI
TRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLY
RLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVV
ESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGF
DVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ
|
| External Links |
|---|
| GenBank ID Protein
| 55665859 |
| UniProtKB/Swiss-Prot ID
| Q5VUC7 |
| UniProtKB/Swiss-Prot Entry Name
| Q5VUC7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AL590365 |
| GeneCard ID
| NMT2 |
| GenAtlas ID
| NMT2 |
| HGNC ID
| HGNC:7858 |
| References |
|---|
| General References
| Not Available |
