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Showing Protein HERV-K_19q12 provirus ancestral Pol protein (HMDBP11889)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP11889
Secondary Accession Numbers None
Name HERV-K_19q12 provirus ancestral Pol protein
Synonyms
  1. HERV-K(C19) Pol protein
Gene Name ERVK6
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA. The RNase H domain of the reverse transcriptase performs two functions. It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid. Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome. Endogenous Pol proteins may have kept, lost or modified their original function during evolution.
Pathways Not Available
Reactions
Deoxynucleoside triphosphate + DNA(n) → Pyrophosphate + DNA(n+1) details
GO Classification
Biological Process
DNA recombination
nucleic acid phosphodiester bond hydrolysis
DNA integration
RNA-dependent DNA replication
Molecular Function
metal ion binding
zinc ion binding
RNA binding
DNA binding
ribonuclease H activity
RNA-directed DNA polymerase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9WJR5
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:13915
References
General References Not Available